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Publications
Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis.
Oncogenesis
Ribosome profiling reveals a functional role for autophagy in mRNA translational control.
Communications biology
Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers.
Cell reports
Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia.
Cancer discovery
Translation control of the immune checkpoint in cancer and its therapeutic targeting.
Nature medicine
A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments.
Nature medicine
Heterogeneous resistance to quizartinib in acute myeloid leukemia revealed by single-cell analysis.
Blood
Establishment and characterization of an oral tongue squamous cell carcinoma cell line from a never-smoking patient.
Oral oncology
Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution.
Scientific reports
Inactivation of Capicua drives cancer metastasis.
Nature genetics
Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma.
Proceedings of the National Academy of Sciences of the United States of America
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
Nature biotechnology
RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.
Nature medicine
Clinical Sequencing Contributes to a BRCA-Associated Cancer Rediagnosis That Guides an Effective Therapeutic Course.
Journal of the National Comprehensive Cancer Network : JNCCN
The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies.
Nature genetics
Synthetic lethality in ATM-deficient RAD50-mutant tumors underlies outlier response to cancer therapy.
Cancer discovery
Mapping the molecular determinants of BRAF oncogene dependence in human lung cancer.
Proceedings of the National Academy of Sciences of the United States of America
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma.
Science (New York, N.Y.)